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Low-cost plant compound, Cytisine, may help people quit smoking: Study | | | Agencies NEW DELHI, Jan 1: Cytisine, a plant-based compound, increases the chances of successful smoking cessation by over two-fold compared with placebo and may be more effective than nicotine replacement therapy, a study has found. Cytisine, a low-cost, generic stop-smoking aid has been used in eastern Europe since the 1960s and has shown no serious safety concerns, the researchers said. However, the compound is not licensed or marketed in most countries outside of central and eastern Europe, making it unavailable in most of the world, including many low- and middle-income (LAMI) countries where it could make a big difference to global health. The study, published in the journal Addiction, pooled the results of eight trials comparing cytisine with placebo, with nearly 6,000 patients. The combined results showed that cytisine increases the chances of successful smoking cessation by more than two-fold compared with placebo, the researchers said. They also noted that cytisine may be more effective than nicotine replacement therapy, a medically approved way to treat people with tobacco use disorder by taking nicotine through means other than tobacco.
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